Variation in PPP3CC Genotype Is Associated with Long-Term Recovery after Severe Brain Injury

After experimental traumatic brain injury (TBI), calcineurin is upregulated; blocking calcineurin is associated with improved outcomes. In humans, variation in the calcineurin A-gamma gene (PPP3CC) has been associated with neuropsychiatric disorders, though any role in TBI recovery remains unknown....

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Pubblicato in:J Neurotrauma
Autori principali: Osier, Nicole D., Bales, James W., Pugh, Bunny, Shin, Samuel, Wyrobek, Julie, Puccio, Ava M., Okonkwo, David O., Ren, Dianxu, Alexander, Sheila, Conley, Yvette P., Dixon, C. Edward
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2017
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5198144/
https://ncbi.nlm.nih.gov/pubmed/27225880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2015.4343
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