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Synthesis, Spatial Structure and Analgesic Activity of Sodium 3-Benzylaminocarbonyl-1-methyl-2,2-dioxo-1H-2λ(6),1-benzothiazin-4-olate Solvates

In order to obtain and then test pharmocologically any possible conformers of the new feasible analgesic N-benzyl-4-hydroxy-1-methyl-2,2-dioxo-1H-2λ(6),1-benzothiazine-3-carboxamide, its 4-O-sodium salt was synthesized using two methods. X-ray diffraction study made possible to determine that, depen...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Pharm
Hauptverfasser: Ukrainets, Igor V., Petrushova, Lidiya A., Shishkina, Svitlana V., Grinevich, Lina A., Sim, Galina
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5198029/
https://ncbi.nlm.nih.gov/pubmed/27775559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/scipharm84040705
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