Absence of the 40-kDa form of (2'-5')oligoadenylate synthetase and its corresponding mRNA from skin fibroblasts derived from Alzheimer disease patients.

Cultured skin fibroblasts derived from Alzheimer disease patients fail to express the 1.6-kilobase (kb) mRNA and the corresponding 40-kDa form of (2'-5')oligoadenylate (2-5A) synthetase when exposed to interferon. In addition, the 3.6-kb mRNA, which is present in normal fibroblasts, is barely detect...

Descrición completa

Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Principais autores:	Khanna, K K, An, S J, Wu, J M, Landolfo, S, Hovanessian, A G
Formato:	Artigo
Idioma:	Inglês
Publicado:	National Academy of Sciences 1991
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51976/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1712108/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.13.5852
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!