Profiling the macrofilaricidal effects of flubendazole on adult female Brugia malayi using RNAseq

The use of microfilaricidal drugs for the control of onchocerciasis and lymphatic filariasis (LF) necessitates prolonged yearly dosing. Prospects for elimination or eradication of these diseases would be enhanced by the availability of a macrofilaricidal drug. Flubendazole (FLBZ), a benzimidazole an...

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Detalhes bibliográficos
Publicado no:Int J Parasitol Drugs Drug Resist
Main Authors: O'Neill, Maeghan, Ballesteros, Cristina, Tritten, Lucienne, Burkman, Erica, Zaky, Weam I., Xia, Jianguo, Moorhead, Andrew, Williams, Steven A., Geary, Timothy G.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Articles from the scientific meeting: "Anthelmintics: From Discovery to Resistance II", pp. 288 - 370,
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5196492/
https://ncbi.nlm.nih.gov/pubmed/27733308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2016.09.005
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