Polymorphism in ion channel genes of Dirofilaria immitis: Relevant knowledge for future anthelmintic drug design

Dirofilaria immitis, a filarial parasite, causes cardiopulmonary dirofilariasis in dogs, cats and wild canids. The macrocyclic lactone (ML) class of drugs has been used to prevent heartworm infection. There is confirmed ML resistance in D. immitis and thus there is an urgent need to find new anthelm...

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Bibliografiska uppgifter
I publikationen:Int J Parasitol Drugs Drug Resist
Huvudupphovsmän: Mani, Thangadurai, Bourguinat, Catherine, Keller, Kathy, Carreton, Elena, Peregrine, Andrew, Prichard, Roger K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2016
Ämnen:
Invited Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5196487/
https://ncbi.nlm.nih.gov/pubmed/27682347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2016.06.003
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