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Proximity does not contribute to activity enhancement in the glucose oxidase–horseradish peroxidase cascade

A proximity effect has been invoked to explain the enhanced activity of enzyme cascades on DNA scaffolds. Using the cascade reaction carried out by glucose oxidase and horseradish peroxidase as a model system, here we study the kinetics of the cascade reaction when the enzymes are free in solution,...

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Publicat a:Nat Commun
Autors principals: Zhang, Yifei, Tsitkov, Stanislav, Hess, Henry
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5196434/
https://ncbi.nlm.nih.gov/pubmed/28004753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13982
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