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Tumor-derived CCL2 mediates resistance to radiotherapy in pancreatic ductal adenocarcinoma

PURPOSE: Local tumor growth is a major cause of morbidity and mortality in nearly 30% of patients with pancreatic ductal adenocarcinoma (PDAC). Radiotherapy (RT) is commonly used for local disease control in PDAC, but efficacy is limited. We studied the impact of selectively intervening on RT-induce...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Kalbasi, Anusha, Komar, Chad, Tooker, Graham M., Liu, Mingen, Lee, Jae W., Gladney, Whitney L., Ben-Josef, Edgar, Beatty, Gregory L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5195913/
https://ncbi.nlm.nih.gov/pubmed/27354473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-0870
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