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Heterologously expressed serotonin 1A receptors couple to muscarinic K+ channels in heart.

In cardiac atrial cells, muscarinic acetylcholine receptors activate a K+ current directly via a guanine nucleotide-binding protein (G protein). Serotonin type 1A receptors may activate a similar pathway in hippocampal neurons. To develop a system in which receptor/G protein/K+ channel coupling can...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Karschin, A, Ho, B Y, Labarca, C, Elroy-Stein, O, Moss, B, Davidson, N, Lester, H A
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1991
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51944/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1905814/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.13.5694
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