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DNA looping and Sp1 multimer links: a mechanism for transcriptional synergism and enhancement.

Using conventional and scanning transmission electron microscopy, we have examined the physical basis of long-range enhancer effects between distal and proximal elements in a eukaryotic promoter. Specifically, we have studied binding of human transcription factor Sp1 to 10-base-pair G+C-rich element...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Mastrangelo, I A, Courey, A J, Wall, J S, Jackson, S P, Hough, P V
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1991
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51939/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2062845/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.13.5670
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