N,N-Dimethylacetamide Significantly Attenuates LPS- and TNFα-Induced Proinflammatory Responses Via Inhibition of the Nuclear Factor Kappa B Pathway

Previously, we have shown that N,N-dimethylacetamide (DMA) prevents inflammation-induced preterm birth in a murine model, inhibits lipopolysaccharide (LPS)-induced increases in placental proinflammatory cytokines and upregulates the antiinflammatory cytokine interleukin-10 (IL-10). However, DMA’s me...

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Detalhes bibliográficos
Publicado no:Mol Med
Main Authors: Pekson, Ryan, Poltoratsky, Vladimir, Gorasiya, Samir, Sundaram, Sruthi, Ashby, Charles R, Vancurova, Ivana, Reznik, Sandra E
Formato: Artigo
Idioma:Inglês
Publicado em: Feinstein Institute for Medical Research 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5193464/
https://ncbi.nlm.nih.gov/pubmed/27782292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2016.00017
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