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Scalpel or Straitjacket: CRISPR/Cas9 Approaches for Muscular Dystrophies

Versatility of CRISPR/Cas9-based platforms makes them promising tools for the correction of diverse genetic/epigenetic disorders. Here we contrast the use of these genome editing tools in two myopathies with very different molecular origins: Duchenne muscular dystrophy, a monogenetic disease, and fa...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Trends Pharmacol Sci
Prif Awduron: Himeda, Charis L., Jones, Takako I., Jones, Peter L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5193161/
https://ncbi.nlm.nih.gov/pubmed/26917062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2016.02.001
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