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Humans with Type-2 Diabetes Show Abnormal Long-Term Potentiation-Like Cortical Plasticity Associated with Verbal Learning Deficits

BACKGROUND: Type-2 diabetes mellitus (T2DM) accelerates cognitive aging and increases risk of Alzheimer’s disease. Rodent models of T2DM show altered synaptic plasticity associated with reduced learning and memory. Humans with T2DM also show cognitive deficits, including reduced learning and memory,...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis
Main Authors: Fried, Peter J., Schilberg, Lukas, Brem, Anna-Katharine, Saxena, Sadhvi, Wong, Bonnie, Cypess, Aaron M., Horton, Edward S., Pascual-Leone, Alvaro
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5193103/
https://ncbi.nlm.nih.gov/pubmed/27636847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-160505
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