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Cbl ubiquitin ligases mediate the inhibition of natural killer cell activity
Natural killer (NK) cells are essential for killing transformed and virally infected cells. To prevent auto-reactivity, NK cell activation is inhibited by inhibitory receptors that activate the tyrosine phosphatase SHP-1, which dephosphorylates signaling molecules crucial for NK cell activation. Ini...
Shranjeno v:
| izdano v: | Commun Integr Biol |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Taylor & Francis
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5193043/ https://ncbi.nlm.nih.gov/pubmed/28042374 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420889.2016.1216739 |
| Oznake: |
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