Afzelin ameliorates D‐galactosamine and lipopolysaccharide‐induced fulminant hepatic failure by modulating mitochondrial quality control and dynamics

BACKGROUND AND PURPOSE: Fulminant hepatic failure (FHF) is a fatal clinical syndrome that results in excessive inflammation and hepatocyte death. Mitochondrial dysfunction is considered to be a possible mechanism of FHF. Afzelin, a flavonol glycoside found in Houttuynia cordata Thunberg, has anti‐in...

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Publicat a:Br J Pharmacol
Autors principals: Lee, Sang‐Bin, Kang, Jung‐Woo, Kim, So‐Jin, Ahn, Jongmin, Kim, Jinwoong, Lee, Sun‐Mee
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
Matèries:
Research Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5192940/
https://ncbi.nlm.nih.gov/pubmed/27861739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13669
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