Evaluation of Methylation Biomarkers for Detection of Circulating Tumor DNA and Application to Colorectal Cancer

Solid tumors shed DNA into circulation, and there is growing evidence that the detection of circulating tumor DNA (ctDNA) has broad clinical utility, including monitoring of disease, prognosis, response to chemotherapy and tracking tumor heterogeneity. The appearance of ctDNA in the circulating cell...

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Veröffentlicht in:Genes (Basel)
Hauptverfasser: Mitchell, Susan M., Ho, Thu, Brown, Glenn S., Baker, Rohan T., Thomas, Melissa L., McEvoy, Aidan, Xu, Zheng-Zhou, Ross, Jason P., Lockett, Trevor J., Young, Graeme P., LaPointe, Lawrence C., Pedersen, Susanne K., Molloy, Peter L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5192501/
https://ncbi.nlm.nih.gov/pubmed/27983717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes7120125
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