Chloroquine, an Endocytosis Blocking Agent, Inhibits Zika Virus Infection in Different Cell Models

Zika virus (ZIKV) infection in utero might lead to microcephaly and other congenital defects. Since no specific therapy is available thus far, there is an urgent need for the discovery of agents capable of inhibiting its viral replication and deleterious effects. Chloroquine is widely used as an ant...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Delvecchio, Rodrigo, Higa, Luiza M., Pezzuto, Paula, Valadão, Ana Luiza, Garcez, Patrícia P., Monteiro, Fábio L., Loiola, Erick C., Dias, André A., Silva, Fábio J. M., Aliota, Matthew T., Caine, Elizabeth A., Osorio, Jorge E., Bellio, Maria, O’Connor, David H., Rehen, Stevens, de Aguiar, Renato Santana, Savarino, Andrea, Campanati, Loraine, Tanuri, Amilcar
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5192383/
https://ncbi.nlm.nih.gov/pubmed/27916837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v8120322
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