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Selection of Resistance to Clarithromycin in Mycobacterium abscessus Subspecies

Mycobacterium abscessus is an emerging pathogen against which clarithromycin is the main drug used. Clinical failures are commonly observed and were first attributed to acquired mutations in rrl encoding 23S rRNA but were then attributed to the intrinsic production of the erm(41) 23S RNA methylase....

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Publicado en:Antimicrob Agents Chemother
Main Authors: Mougari, Faiza, Bouziane, Feriel, Crockett, Flora, Nessar, Rachid, Chau, Françoise, Veziris, Nicolas, Sapriel, Guillaume, Raskine, Laurent, Cambau, Emmanuelle
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5192163/
https://ncbi.nlm.nih.gov/pubmed/27799212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00943-16
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