Acinetobacter baumannii Biofilm Formation in Human Serum and Disruption by Gallium

Biofilm-associated infections caused by Acinetobacter baumannii are extremely recalcitrant to antibiotic treatment. We report that A. baumannii develops a mature biofilm when grown in complement-free human serum (HS). We demonstrate that 16 μM gallium nitrate (GaN) drastically reduces A. baumannii g...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Runci, Federica, Bonchi, Carlo, Frangipani, Emanuela, Visaggio, Daniela, Visca, Paolo
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2016
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Mechanisms of Action: Physiological Effects
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5192145/
https://ncbi.nlm.nih.gov/pubmed/27799219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01563-16
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