Acquisition of Carbapenem Resistance by Plasmid-Encoded-AmpC-Expressing Escherichia coli

Although AmpC β-lactamases can barely degrade carbapenems, if at all, they can sequester them and prevent them from reaching their targets. Thus, carbapenem resistance in Escherichia coli and other Enterobacteriaceae can result from AmpC production and simultaneous reduction of antibiotic influx int...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: van Boxtel, Ria, Wattel, Agnes A., Arenas, Jesús, Goessens, Wil H. F., Tommassen, Jan
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2016
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5192137/
https://ncbi.nlm.nih.gov/pubmed/27799202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01413-16
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