Competitive Growth Enhances Conditional Growth Mutant Sensitivity to Antibiotics and Exposes a Two-Component System as an Emerging Antibacterial Target in Burkholderia cenocepacia

Chemogenetic approaches to profile an antibiotic mode of action are based on detecting differential sensitivities of engineered bacterial strains in which the antibacterial target (usually encoded by an essential gene) or an associated process is regulated. We previously developed an essential-gene...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Gislason, April S., Choy, Matthew, Bloodworth, Ruhi A. M., Qu, Wubin, Stietz, Maria S., Li, Xuan, Zhang, Chenggang, Cardona, Silvia T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5192132/
https://ncbi.nlm.nih.gov/pubmed/27799222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00790-16
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