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Protective Effects of Human and Mouse Soluble Scavenger-Like CD6 Lymphocyte Receptor in a Lethal Model of Polymicrobial Sepsis

Sepsis still constitutes an unmet clinical need, which could benefit from novel adjunctive strategies to conventional antibiotic therapy. The soluble form of the scavenger-like human CD6 lymphocyte receptor (shCD6) binds to key pathogenic components from Gram-positive and -negative bacteria and show...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Martínez-Florensa, Mario, Consuegra-Fernández, Marta, Aranda, Fernando, Armiger-Borràs, Noelia, Di Scala, Marianna, Carrasco, Esther, Pachón, Jerónimo, Vila, Jordi, González-Aseguinolaza, Gloria, Lozano, Francisco
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5192129/
https://ncbi.nlm.nih.gov/pubmed/27895015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01391-16
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