Evaluating Polymyxin B-Based Combinations against Carbapenem-Resistant Escherichia coli in Time-Kill Studies and in a Hollow-Fiber Infection Model

Polymyxin B-based combinations have emerged as a mainstay treatment against carbapenem-resistant Escherichia coli (CREC). We investigated the activity of polymyxin B-based two-antibiotic combinations against CREC using time-kill studies (TKS) and validated the findings in a hollow-fiber infection mo...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Cai, Yiying, Lim, Tze-Peng, Teo, Jocelyn Qi-Min, Sasikala, Suranthran, Chan, Eric Chun Yong, Hong, Yan Jun, Lee, Winnie, Tan, Thean Yen, Tan, Thuan Tong, Koh, Tse Hsien, Hsu, Li Yang, Kwa, Andrea L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Susceptibility
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5192126/
https://ncbi.nlm.nih.gov/pubmed/27795375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01509-16
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