C-terminal-truncated HBV X promotes hepato-oncogenesis through inhibition of tumor-suppressive β-catenin/BAMBI signaling

C-terminal-truncated hepatitis B virus (HBV) X (HBx) (ctHBX) is frequently detected in hepatocellular carcinoma (HCC) through HBV integration into the host genome. However, the molecular mechanisms underlying ctHBx-associated oncogenic signaling have not yet been clarified. To elucidate the biologic...

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Publicat a:Exp Mol Med
Autors principals: Lee, Seok, Lee, Mi-Jin, Zhang, Jun, Yu, Goung-Ran, Kim, Dae-Ghon
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5192070/
https://ncbi.nlm.nih.gov/pubmed/27909336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2016.107
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