All-trans retinoic acid enhances cytotoxic effect of T cells with an anti-CD38 chimeric antigen receptor in acute myeloid leukemia

We reported that T cells with anti-CD38-chimeric antigen receptors (CAR) eliminated B-cell lymphoma cells expressing CD38. To employ anti-CD38-CAR against acute myeloid leukemia (AML) blasts not expressing CD38, it is necessary to induce or increase the intensity of CD38 expression. A lactate dehydr...

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Detalhes bibliográficos
Publicado no:Clin Transl Immunology
Main Authors: Yoshida, Tetsumi, Mihara, Keichiro, Takei, Yoshifumi, Yanagihara, Kazuyoshi, Kubo, Takanori, Bhattacharyya, Joyeeta, Imai, Chihaya, Mino, Tatsuji, Takihara, Yoshihiro, Ichinohe, Tatsuo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5192064/
https://ncbi.nlm.nih.gov/pubmed/28090317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cti.2016.73
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