Greater activation of peripheral T follicular helper cells following high dose influenza vaccine in older adults forecasts seroconversion

BACKGROUND: Influenza related morbidity and mortality disproportionately impacts older adults. The serologic response to vaccine is diminished in older adults; however, high dose inactivated influenza vaccine (HD IIV) has shown improved rates of seroconversion compared to standard dose (SD IIV). We...

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Enregistré dans:
Détails bibliographiques
Publié dans:Vaccine
Auteurs principaux: Pilkinton, Mark A., Nicholas, Katherine J., Warren, Christian M., Smith, Rita M., Yoder, Sandra M., Talbot, H. Keipp, Kalams, Spyros A.
Format: Artigo
Langue:Inglês
Publié: 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5191956/
https://ncbi.nlm.nih.gov/pubmed/27919633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2016.11.059
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