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Intracellular trafficking of a pH-responsive drug metal complex

We previously developed a pH-responsive copper-doxorubicin (CuDox) cargo in lysolipid-based temperature-sensitive liposomes (LTSLs). The CuDox complex is released from the particle by elevated temperature; however, full release of doxorubicin from CuDox requires a reduced pH, such as that expected i...

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Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Kheirolomoom, Azadeh, Ingham, Elizabeth S., Commisso, Joel, Abushaban, Neveen, Ferrara, Katherine W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5191948/
https://ncbi.nlm.nih.gov/pubmed/27746275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2016.10.012
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