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Determination of β-hydroxy-β-methylbutyrate concentration and enrichment in human plasma using chemical ionization gas chromatography tandem mass spectrometry

Our objective was to develop a quick and simplified method for the determination of β-Hydroxy-β-methylbutyrate (HMB) and α-ketoisocaproic acid (KIC) concentrations and enrichments by GC/MS/MS to determine the turnover rate of HMB in humans. In experiment 1, we provided a pulse of L-[5,5,5-(2)H(3)]le...

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書目詳細資料
發表在:J Chromatogr B Analyt Technol Biomed Life Sci
Main Authors: Walker, Dillon K., Thaden, John J., Wierzchowska-McNew, Agata, Engelen, Marielle P.K.J., Deutz, Nicolaas E.P.
格式: Artigo
語言:Inglês
出版: 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5191936/
https://ncbi.nlm.nih.gov/pubmed/27856194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2016.11.010
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