A rapidly-acting glutamatergic ARC→PVH satiety circuit postsynaptically regulated by α-MSH

Arcuate nucleus (ARC) neurons sense the fed/fasted state and regulate hunger. Agouti-related protein (ARC(AgRP)) neurons are stimulated by fasting, and once activated, they rapidly (within minutes) drive hunger. Pro-opiomelanocortin (ARC(POMC)) neurons are viewed as the counterpoint to ARC(AgRP) neu...

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Gepubliceerd in:Nat Neurosci
Hoofdauteurs: Fenselau, Henning, Campbell, John N., Verstegen, Anne M.J., Madara, Joseph C., Xu, Jie, Shah, Bhavik P., Resch, Jon M., Yang, Zongfang, Mandelblat-Cerf, Yael, Livneh, Yoav, Lowell, Bradford B.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5191921/
https://ncbi.nlm.nih.gov/pubmed/27869800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.4442
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