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A Critical Role of Tropomyosins in TGF-β Regulation of the Actin Cytoskeleton and Cell Motility in Epithelial Cells

We have investigated transforming growth factor beta (TGF-β)–mediated induction of actin stress fibers in normal and metastatic epithelial cells. We found that stress fiber formation requires de novo protein synthesis, p38Mapk and Smad signaling. We show that TGF-β via Smad and p38Mapk up-regulates...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bakin, Andrei V., Safina, Alfiya, Rinehart, Cammie, Daroqui, Cecilia, Darbary, Huferesh, Helfman, David M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC519159/
https://ncbi.nlm.nih.gov/pubmed/15317845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-04-0353
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