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Enhanced Membrane Fusion in Sterol-enriched Vacuoles Bypasses the Vrp1p Requirement

Organization of lipids into membrane microdomains is a vital mechanism of protein processing. Here we show that overexpression of ERG6, a gene involved in ergosterol synthesis, elevates sterol levels 1.5-fold on the vacuole membrane and enhances their homotypic fusion. The mechanism of sterol-enhanc...

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Détails bibliographiques
Auteurs principaux: Tedrick, Kelly, Trischuk, Tim, Lehner, Richard, Eitzen, Gary
Format: Artigo
Langue:Inglês
Publié: The American Society for Cell Biology 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC519153/
https://ncbi.nlm.nih.gov/pubmed/15254266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-03-0194
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