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Enhanced Membrane Fusion in Sterol-enriched Vacuoles Bypasses the Vrp1p Requirement
Organization of lipids into membrane microdomains is a vital mechanism of protein processing. Here we show that overexpression of ERG6, a gene involved in ergosterol synthesis, elevates sterol levels 1.5-fold on the vacuole membrane and enhances their homotypic fusion. The mechanism of sterol-enhanc...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC519153/ https://ncbi.nlm.nih.gov/pubmed/15254266 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-03-0194 |
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