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Conformational Defects Slow Golgi Exit, Block Oligomerization, and Reduce Raft Affinity of Caveolin-1 Mutant Proteins

Caveolin-1, a structural protein of caveolae, is cleared unusually slowly from the Golgi apparatus during biosynthetic transport. Furthermore, several caveolin-1 mutant proteins accumulate in the Golgi apparatus. We examined this behavior further in this mutant study. Golgi accumulation probably res...

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Detalhes bibliográficos
Main Authors: Ren, Xiaoyan, Ostermeyer, Anne G., Ramcharan, Lynne T., Zeng, Youchun, Lublin, Douglas M., Brown, Deborah A.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC519149/
https://ncbi.nlm.nih.gov/pubmed/15304521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-06-0480
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