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Potent cytodifferentiating agents related to hexamethylenebisacetamide.

Bishydroxamic acids are effective inducers of differentiation in murine erythroleukemia cells. Flexible analogs of suberic acid bisdimethylamide are approximately 100 times as active as the parent compound or hexamethylenebisacetamide. They also induce differentiation of human promyelocytic leukemia...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Breslow, R, Jursic, B, Yan, Z F, Friedman, E, Leng, L, Ngo, L, Rifkind, R A, Marks, P A
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51913/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2062836/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.13.5542
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