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Improving specificity of DNA hybridization-based methods
Methods based on DNA reassociation in solution with the subsequent PCR amplification of certain hybrid molecules, such as coincidence cloning and subtractive hybridization, all suffer from a common imperfection: cross-hybridization between various types of paralogous repetitive DNA fragments. Althou...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2004
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC519126/ https://ncbi.nlm.nih.gov/pubmed/15371554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gnh125 |
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