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Identifying DNA-binding proteins using structural motifs and the electrostatic potential

Robust methods to detect DNA-binding proteins from structures of unknown function are important for structural biology. This paper describes a method for identifying such proteins that (i) have a solvent accessible structural motif necessary for DNA-binding and (ii) a positive electrostatic potentia...

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Autori principali: Shanahan, Hugh P., Garcia, Mario A., Jones, Susan, Thornton, Janet M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC519102/
https://ncbi.nlm.nih.gov/pubmed/15356290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh803
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