Observation of the light-triggered binding of pyrone to chymotrypsin by Laue x-ray crystallography.
Crystals of gamma-chymotrypsin inhibited with the photodissociable group trans-p-diethylamino-o-hydroxy-alpha-methylcinnamate were irradiated with a 1-msec flash from a high-energy xenon flashlamp in the presence of the mechanism-based inhibitor 3-benzyl-6-chloro-2-pyrone. The ensuing reaction was m...
Guardat en:
| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1991
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51905/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2062832/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.13.5503 |
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