Molecular and clinical significance of fibroblast growth factor 2 (FGF2 /bFGF) in malignancies of solid and hematological cancers for personalized therapies

Fibroblast growth factor (FGF) signaling is essential for normal and cancer biology. Mammalian FGF family members participate in multiple signaling pathways by binding to heparan sulfate and FGF receptors (FGFR) with varying affinities. FGF2 is the prototype member of the FGF family and interacts wi...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Akl, Mohamed R., Nagpal, Poonam, Ayoub, Nehad M., Tai, Betty, Prabhu, Sathyen A., Capac, Catherine M., Gliksman, Matthew, Goy, Andre, Suh, K. Stephen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
Soggetti:
Review
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5190132/
https://ncbi.nlm.nih.gov/pubmed/27007053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8203
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