TGF-β1 contributes to CD8(+) Treg induction through p38 MAPK signaling in ovarian cancer microenvironment

CD8(+) regulatory T cells (Tregs) contribute to cancer progression and immune evasion. We previously reported that CD8(+) Tregs could be induced in vitro by co-culture of CD8(+) T cells with the OC cell lines SKOV3/A2780. Here, we described the role of TGF-β1 in CD8(+) Treg induction by the OC micro...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wu, Meng, Chen, Xian, Lou, Jianfang, Zhang, Shuping, Zhang, Xiaojie, Huang, Lei, Sun, Ruihong, Huang, Peijun, Wang, Fang, Pan, Shiyang
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5190116/
https://ncbi.nlm.nih.gov/pubmed/27322208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10003
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