SPANXA suppresses EMT by inhibiting c-JUN/SNAI2 signaling in lung adenocarcinoma

SPANXA (Sperm Protein Associated with the Nucleus on the X-chromosome, family members A1/A2) acts as a cancer-testis antigen expressed in normal testes, but dysregulated in various tumors. We found that SPANXA is highly expressed in low-invasive CL1-0 cells compared with isogenous high-invasive CL1-...

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Pubblicato in:Oncotarget
Autori principali: Hsiao, Yi-Jing, Su, Kang-Yi, Hsu, Yi-Chiung, Chang, Gee-Chen, Chen, Jin-Shing, Chen, Hsuan-Yu, Hong, Qi-Sheng, Hsu, Shih-Chun, Kang, Po-Hsiang, Hsu, Chia-Ying, Ho, Bing-Ching, Yang, Tsung-Hui, Wang, Chia-Yu, Jou, Yuh-Shan, Yang, Pan-Chyr, Yu, Sung-Liang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5190107/
https://ncbi.nlm.nih.gov/pubmed/27323831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10088
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