Demonstration of potential link between Helicobacter pylori related promoter CpG island methylation and telomere shortening in human gastric mucosa

BACKGROUND: Telomere length shortening in Helicobacter pylori (H. pylori) infected gastric mucosa constitutes the earliest steps toward neoplastic transformation. In addition to this genotoxic changes, epigenetic changes such as promoter CpG island (PCGI) methylation are frequently occurred in H. py...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Tahara, Tomomitsu, Shibata, Tomoyuki, Okubo, Masaaki, Kawamura, Tomohiko, Horiguchi, Noriyuki, Ishizuka, Takamitsu, Nakano, Naoko, Nagasaka, Mitsuo, Nakagawa, Yoshihito, Ohmiya, Naoki
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5190073/
https://ncbi.nlm.nih.gov/pubmed/27259265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9764
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