Orai1 promotes tumor progression by enhancing cancer stemness via NFAT signaling in oral/oropharyngeal squamous cell carcinoma

Emerging evidence indicates that Orai1, a key calcium channel for store-operated Ca(2+) entry, is associated with human cancer. However, the underlying mechanism by which Orai1 regulates cancer progression remains unknown. Here we report that intracellular level of Orai1 is increased in a stepwise m...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Lee, Sung Hee, Rigas, Nicole Kristina, Lee, Chang-Ryul, Bang, April, Srikanth, Sonal, Gwack, Yousang, Kang, Mo K., Kim, Reuben H., Park, No-Hee, Shin, Ki-Hyuk
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5190020/
https://ncbi.nlm.nih.gov/pubmed/27259269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9755
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