Epithelial ovarian cancer-secreted exosomal miR-222-3p induces polarization of tumor-associated macrophages

Cancer secreted exosomal miRNAs are emerging as mediators between tumor-stoma crosstalk. Here, we show epithelial ovarian cancer (EOC)-derived exosomes activated macrophages to a tumor-associated macrophage (TAM)-like phenotype with SOCS3/STAT3 pathway involvement, which could facilitate the progres...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Ying, Xiang, Wu, Quanfeng, Wu, Xiaoli, Zhu, Qinyi, Wang, Xinjing, Jiang, Lu, Chen, Xin, Wang, Xipeng
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5190009/
https://ncbi.nlm.nih.gov/pubmed/27172798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9246
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