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Polyplexes assembled from self-peptides and regulatory nucleic acids blunt toll-like receptor signaling to combat autoimmunity

Autoimmune diseases occur when the immune system incorrectly recognize self-molecules as foreign; in the case of multiple sclerosis (MS), myelin is attacked. Intriguingly, new studies reveal toll-like receptors (TLR), pathways usually involved in generating immune response again pathogens, play a si...

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Detalhes bibliográficos
Publicado no:Biomaterials
Main Authors: Hess, Krystina L., Andorko, James I., Tostanoski, Lisa H., Jewell, Christopher M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5189983/
https://ncbi.nlm.nih.gov/pubmed/27940382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2016.11.052
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