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A novel synthetic Asiatic acid derivative induces apoptosis and inhibits proliferation and mobility of gastric cancer cells by suppressing STAT3 signaling pathway

Activation of the transcription factor, signal transducers and activators of transcription 3 (STAT3), has been linked to the proliferation and migration of a variety of human cancer cells. These actions occur via the upregulation or downregulation of cell survival and tumor suppressor genes, respect...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Wang, Gang, Jing, Yue, Cao, Lingsen, Gong, Changchang, Gong, Zhunan, Cao, Xiangrong
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5189974/
https://ncbi.nlm.nih.gov/pubmed/28053540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S121619
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