Elevated Fibroblast Growth Factor Signaling Is Critical for the Pathogenesis of the Dwarfism in Evc2/Limbin Mutant Mice

Ellis-van Creveld (EvC) syndrome is a skeletal dysplasia, characterized by short limbs, postaxial polydactyly, and dental abnormalities. EvC syndrome is also categorized as a ciliopathy because of ciliary localization of proteins encoded by the two causative genes, EVC and EVC2 (aka LIMBIN). While r...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS Genet
Egile Nagusiak: Zhang, Honghao, Kamiya, Nobuhiro, Tsuji, Takehito, Takeda, Haruko, Scott, Greg, Rajderkar, Sudha, Ray, Manas K., Mochida, Yoshiyuki, Allen, Benjamin, Lefebvre, Veronique, Hung, Irene H., Ornitz, David M., Kunieda, Tetsuo, Mishina, Yuji
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2016
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5189957/
https://ncbi.nlm.nih.gov/pubmed/28027321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006510
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