Genomic Analysis of Uterine Lavage Fluid Detects Early Endometrial Cancers and Reveals a Prevalent Landscape of Driver Mutations in Women without Histopathologic Evidence of Cancer: A Prospective Cross-Sectional Study

BACKGROUND: Endometrial cancer is the most common gynecologic malignancy, and its incidence and associated mortality are increasing. Despite the immediate need to detect these cancers at an earlier stage, there is no effective screening methodology or protocol for endometrial cancer. The comprehensi...

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Wydane w:PLoS Med
Główni autorzy: Nair, Navya, Camacho-Vanegas, Olga, Rykunov, Dmitry, Dashkoff, Matthew, Camacho, Sandra Catalina, Schumacher, Cassie A., Irish, Jonathan C., Harkins, Timothy T., Freeman, Elijah, Garcia, Isaac, Pereira, Elena, Kendall, Sviatoslav, Belfer, Rachel, Kalir, Tamara, Sebra, Robert, Reva, Boris, Dottino, Peter, Martignetti, John A.
Format: Artigo
Język:Inglês
Wydane: Public Library of Science 2016
Hasła przedmiotowe:
Research Article
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5189938/
https://ncbi.nlm.nih.gov/pubmed/28027320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1002206
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