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Paradoxical antifungal activity and structural observations in biofilms formed by echinocandin-resistant Candida albicans clinical isolates

Echinocandin-resistant clinical isolates of Candida albicans have been reported, and key-hot spot mutations in the FKS1 gene, which encodes a major glucan synthase subunit, have been identified in these (caspofungin-resistant [CAS-R]) strains. Although these mutations result in phenotypic resistance...

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發表在:Med Mycol
Main Authors: Walraven, Carla J., Bernardo, Stella M., Wiederhold, Nathan P., Lee, Samuel A.
格式: Artigo
語言:Inglês
出版: 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5189660/
https://ncbi.nlm.nih.gov/pubmed/24576999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/mmy/myt007
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