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What is the impact of the ACE gene insertion/deletion (I/D) polymorphism on the clinical effectiveness and adverse events of ACE inhibitors? – Protocol of a systematic review

BACKGROUND: The Angiotensin Converting Enzyme (ACE) insertion/deletion (I/D) polymorphism has received much attention in pharmacogenetic research because observed variations in response to ACE inhibitors might be associated with this polymorphism. Pharmacogenetic testing raises the hope to individua...

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Autori principali: Scharplatz, M, Puhan, MA, Steurer, J, Bachmann, LM
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC518966/
https://ncbi.nlm.nih.gov/pubmed/15361261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-5-23
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