Platelet-Derived Growth Factor-BB Protects Mesenchymal Stem Cells (MSCs) Derived From Immune Thrombocytopenia Patients Against Apoptosis and Senescence and Maintains MSC-Mediated Immunosuppression

Immune thrombocytopenia (ITP) is characterized by platelet destruction and megakaryocyte dysfunction. Mesenchymal stem cells (MSCs) from ITP patients (MSC-ITP) do not exhibit conventional proliferative abilities and thus exhibit defects in immunoregulation, suggesting that MSC impairment might be a...

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Detalhes bibliográficos
Publicado no:Stem Cells Transl Med
Main Authors: Zhang, Jia-min, Feng, Fei-er, Wang, Qian-ming, Zhu, Xiao-lu, Fu, Hai-xia, Xu, Lan-ping, Liu, Kai-yan, Huang, Xiao-jun, Zhang, Xiao-hui
Formato: Artigo
Idioma:Inglês
Publicado em: AlphaMed Press 2016
Assuntos:
Tissue-Specific Progenitor and Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5189646/
https://ncbi.nlm.nih.gov/pubmed/27471307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2015-0360
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