Clinical Actionability of Comprehensive Genomic Profiling for Management of Rare or Refractory Cancers

BACKGROUND. The frequency with which targeted tumor sequencing results will lead to implemented change in care is unclear. Prospective assessment of the feasibility and limitations of using genomic sequencing is critically important. METHODS. A prospective clinical study was conducted on 100 patient...

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Publicado en:Oncologist
Main Authors: Hirshfield, Kim M., Tolkunov, Denis, Zhong, Hua, Ali, Siraj M., Stein, Mark N., Murphy, Susan, Vig, Hetal, Vazquez, Alexei, Glod, John, Moss, Rebecca A., Belyi, Vladimir, Chan, Chang S., Chen, Suzie, Goodell, Lauri, Foran, David, Yelensky, Roman, Palma, Norma A., Sun, James X., Miller, Vincent A., Stephens, Philip J., Ross, Jeffrey S., Kaufman, Howard, Poplin, Elizabeth, Mehnert, Janice, Tan, Antoinette R., Bertino, Joseph R., Aisner, Joseph, DiPaola, Robert S., Rodriguez-Rodriguez, Lorna, Ganesan, Shridar
Formato: Artigo
Idioma:Inglês
Publicado: AlphaMed Press 2016
Assuntos:
Cancer Diagnostics and Molecular Pathology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5189630/
https://ncbi.nlm.nih.gov/pubmed/27566247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2016-0049
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