Clinical Actionability of Comprehensive Genomic Profiling for Management of Rare or Refractory Cancers

BACKGROUND. The frequency with which targeted tumor sequencing results will lead to implemented change in care is unclear. Prospective assessment of the feasibility and limitations of using genomic sequencing is critically important. METHODS. A prospective clinical study was conducted on 100 patient...

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Udgivet i:Oncologist
Main Authors: Hirshfield, Kim M., Tolkunov, Denis, Zhong, Hua, Ali, Siraj M., Stein, Mark N., Murphy, Susan, Vig, Hetal, Vazquez, Alexei, Glod, John, Moss, Rebecca A., Belyi, Vladimir, Chan, Chang S., Chen, Suzie, Goodell, Lauri, Foran, David, Yelensky, Roman, Palma, Norma A., Sun, James X., Miller, Vincent A., Stephens, Philip J., Ross, Jeffrey S., Kaufman, Howard, Poplin, Elizabeth, Mehnert, Janice, Tan, Antoinette R., Bertino, Joseph R., Aisner, Joseph, DiPaola, Robert S., Rodriguez-Rodriguez, Lorna, Ganesan, Shridar
Format: Artigo
Sprog:Inglês
Udgivet: AlphaMed Press 2016
Fag:
Cancer Diagnostics and Molecular Pathology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5189630/
https://ncbi.nlm.nih.gov/pubmed/27566247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2016-0049
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